Most people, I imagine, grab whateverâs cheapest, or closest, or whatever they always use. But if youâre scrupulous enough to ask Google for the best painkiller, hereâs how your friendly neighbourhood tech behemoth would answer:
Oh, thanks, Googleâthatâs just all of them.
If youâre among the 77% of Americans that Google their health problems, insipid answers like this wonât surprise you. But we should be surprised because researchers carry out tens of thousands of clinical trials every year. And hundreds of clinical trials have examined the effectiveness of painkillers. So why canât I Google those results?
And so in the year of our lord 2017 I had a brilliant startup idea: Use a structured database of clinical trials to provide simple, practical answers to common medical questions.
As a proof-of-concept I tried this by hand: I made a spreadsheet with every OTC painkiller trial I could find and used R to run a network meta-analysis, the gold standard of evidence-based medicine.
The results were pretty interesting, and exactly the kind of thing I was looking for back in the sad, sterile aisles of CVS:
Results from my first meta-analysis (157 trials, 4,400 people).
A wave of exhilaration washed over me. Here was a problem that:
- Was interesting
- Could help people
- I knew how to solve
A perfect bullseye. After a few hours searching domains I came up with a name for my project: GlacierMD.
Over the next nine months, I would quit my job, write over 200,000 lines of code, hire five contractors, create a Delaware C-Corp, add four doctors to my advisory board, and demo GlacierMD for 12 Bay Area medical practices. I would spend $40,000 of my own savings buying clinical trials and paying contractors to enter said trials into the GlacierMD database.
On July 2, 2018, GlacierMD powered the worldâs largest depression meta-analysis, using data from 846 trials, beating Ciprianiâs previous record of 522.
GlacierMDâs evidence graph for depression treatments.
Choirs of angels sang in my ears. Here I was, living the Silicon Valley dream, making the world a better place through technology.
Two weeks later GlacierMD was dead.
âThatâs an awesome idea,â Carl said. âIt sounds like something worth working on.â
Carl was my boss. We worked at a startup that leveraged autonomous blockchains to transfer money from naĂŻve investors to slightly less naĂŻve twentysomethings. There are worse gigs.
And here was Carl telling me that my startup idea would bring such benefit to humanity that I simply had to quit, his roadmap be damned. I nodded knowingly, feeling the weight of this responsibility resting on my proud shoulders.
âThanks Carl,â I said. âIâll try to mention you when I accept my Nobel.â
I quit two weeks later and started coding at a blistering pace. I drew all sorts of inscrutable diagrams with dry-erase pens on my parentsâ windows. I hired a motley crew of Egyptian contractors to start entering clinical trials into my database. I commissioned a logo, registered my domain, and started obsessing over colour schemes.
Data extraction portal for GlacierMD.
When I finally finished the MVP, I showed it to the head of product at the company Iâd just left. I watched him as he watched my demo, waiting for his eyes to melt with the glory of it all. Instead, he just sorta shrugged.
âLots of people make medical claims on the internet,â he said. âWhy should I trust yours?â
I started babbling about network meta-analyses, statistical power, and p-values, but he cut me off.
âYeah okay thatâs great, but nobody cares about this math crap. You need doctors.â
Goddamnit, he was right. If nobody could be bothered with the math, then I was no better than Gwenyth Paltrow hawking vagina eggs. To build trust, I needed to get endorsements from trustworthy people.
So I called up some friends, some buddies, some friends-of-friends. âWould you like to be an advisor for my cutting-edge health-tech startup?â Iâd ask while eating Dominos in my parentsâ laundry room. Iâd give them 1% of this extremely valuable, high-growth startup, and in exchange, I could plaster their faces all over my website.
Four of these doctors agreed. This is called making deals, ladies and gentlemen, and I was like the lovechild of Warren Buffet and Dr Oz.
Things are going great. My friends and family all tell me they love the site. Even some strangers on the internet love it. âI know right,â I tell them. âSo how much would you pay for this?â
âHahahahahahah,â they say in unison. âGood one!â
I forgot that the first law of consumer tech is nobody pays for consumer tech. But no problemo, I say to myself. This is why Eric Schmidt invented ads. Iâll just plaster a few banners on GlacierMD and bing bang boom Iâll be seasteading with Peter Thiel before Burning Man.
But then I look at WebMDâs 10-Qs and start to spiral. Turns out, the worldâs biggest health website makes about $0.50/year per user. That is⊠not enough money to bootstrap GlacierMD. Iâm pouring money into my rent, into my Egyptian contractors, into AWS â I need some cash soon.
What I need are people willing to pay for this thing. What about doctors? Doctors have money, right? Maybe doctors, or practices, or whatever â someone in the medical industry â maybe they would shell out some cash for my on-demand meta-analyses.
So I listened to a few podcasts and became a sales expert. I started cold-calling people using scripts from the internet and tried to convince them to sit through a GlacierMD demo.
In the meantime, I receive some worrying messages from my Egyptian contractors.
âI think itâs time to talk about a raise,â one of them says.
âI feel that I have become exceptional at my job,â says another. âPlease consider a raise or I will stop working.â
âPlease increase my pay,â says the third, including helpful screenshots demonstrating how to give said raise through the Upwork website.
Are my contractors unionizing? I wonder. I glance obliquely at my shrinking bank account statement, grit my teeth, and approve the raises. At this rate, Iâll hit zero in a matter of weeks.
But my sales calls start paying off. Miraculously, I find some doctors that are willing to talk to me. So I borrow my parentsâ car and drive out to the burbs to meet a doctor Iâll call Susan.
Susan has a small practice in downtown Redwood City, a Silicon Valley town that looks 3D printed from the Google Image results for âmain street.â
Susan is a bit chatty (sheâs a psychiatrist), but eventually I demo GlacierMD. I show her how you can filter studies based on the demographic data of the patient, how you can get treatment recommendations based on a preferred side effect profile, how you can generate a dose-response curve. She oohs and aahs at all the right points. By the end of the interview, sheâs practically drooling.
Comparing the efficacy of two antidepressants over time.
Hook, line, and sinker, I think to myself. Iâm already contemplating what colour Away bags would look best in the back of my Cybertruck when Susan interrupts my train of thought.
âWhat a fun project!â she says enthusiastically.
Something in her tone makes me pause. âUh, yeah,â I say. âSo what would you imagine a product like this â one that could change the very practice of medicine â how much would you pay for such a service?â
âOh, uh â hmm,â she said. âI donât know if we can spare the budget here, to be honest. Itâs very fun⊠but Iâm not sure if our practice can justify this cost.â
If you read enough sales books most of them tell you that when people say your product is too expensive, what they really mean is your product isnât valuable enough. Susan acted like I was offering her Nirvana as a service, so the conversation has taken quite a wild turn.
âSo you donât think this product is useful?â
âOh, sure! I mean, I think in many cases Iâll just prescribe what I normally do since Iâm comfortable with it. But you know itâs possible that sometimes Iâll prescribe something different, based on your meta-studies.â
âAnd that isnât worth something? Prescribing better treatments?â
âHmmm,â she said, picking at her fingernails. âNot directly. Of course, I always have the best interests of my patients in mind, but, you know, itâs not like theyâll pay more if I prescribe Lexapro instead of Zoloft. They wonât come back more often or refer more friends. So Iâd sorta just be, like, donating this money if I paid you for this thing, right?â
I had literally nothing to say to that. It had been a bit of a working assumption of mine over the past few weeks that if you could improve the health of the patients then, you know, the doctors or the hospitals or whatever would pay for that. There was this giant thing called health care, and its main purpose is improving health â trillions of dollars are spent trying to do this. So if I built I thing that improves health, someone should pay me, right?
I said goodbye to Susan and tried to cheer myself up. I had 10 more meetings with doctors all over the Bay Area â surely not all of them were ruthless capitalists like Susan. Maybe they would see the towering genius of GlacierMD and shell out some cash.
But in fact, everyone gave me some version of Susanâs answer. âWe just canât justify the cost,â a pediatrician told me. âIâm not sure itâs in the budget,â said a primary care physician. âItâs awesome,â said a hospitalist. âYou should try to sell this!â Ugh.
So in July 2018, nine months and $40,000 after starting GlacierMD, I shut it down. I fired my contractors, archived the database, and shut down the servers. GlacierMD was dead.
Make something people want. Itâs YCombinatorâs motto and a maxim of aspiring internet entrepreneurs. The idea is that if you build something truly awesome, youâll figure out a way to make some money off of it.
So I built something people wanted. Consumers wanted it, doctors wanted it, I wanted it. Where did I go wrong?
Occasionally, I like to disconnect from the IV drip of internet pseudo-knowledge and learn stuff from books. I know, itâs weird â maybe even a bit hipster. But recently I read Whartonâs introductory marketing textbook, Strategic Marketing Management. The very first chapter has this to say:
To succeed, an offering must create value for all entities involved in the exchange - target customers, the company, and its collaborators.
All stakeholders. You canât just create value for the user: Thatâs a charity. You also canât just create value for your company: Thatâs a scam. Your goal is to set up some kind of positive-sum exchange where everyone benefits, including you. A business plan, according to this textbook, starts with this simple question: How will you create value for yourself and the company?
What they teach you in business school.
I winced audibly when I read this. How much time I couldâve saved! If Iâd articulated at the beginning how I expected to extract value from GlacierMD, maybe I wouldâve researched the economics of an ad-based model, or I wouldâve validated that doctors were willing to pay, or hospitals, or insurance companies.
A few months after shuttering GlacierMD and returning to corporate life, my buddy pitched me a new startup idea.
âItâs called Doppelganger,â he said. âItâs super simple â you upload a selfie to the database, and then it uses AI or whatever to instantly find everyone in the database who â â
âLooks like you,â I finished for him.
âExactly,â he said, grinning ear to ear. âHow awesome would that be? You should build it!â
I mean, I dunno, it sounds like something fun to do at parties. In a narrow sense, itâs something I want, but thereâs no way in hell Iâm going to devote any time to this. Doppelganger has created value for the customer but not for the company.
âCall me when you have a business plan,â I said, lacing up my Allbirds before and riding my Lime scooter into the sunset.
This post originally appeared on the authorâs personal blog. Tom Cleveland is a Software Engineer at Stripe in San Francisco who also writes occasionally on entrepreneurship.